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Mutations in genes drive cancer by rewiring normal biological processes. It is now clear that multiple mutations occur in most cancers. We are working to understand how these mutations cooperate to drive cancer initiation and progression, both to decipher the biological basis of cancer and to develop new therapeutic approaches. Our overarching goal is to use this information to reverse engineer cancer to develop more effective, less toxic therapies.
To achieve this goal, Dr. Hahn has assembled a multi-disciplinary group composed of oncologists, geneticists, biochemists and computational scientists who work collaboratively to create cutting edge, systematic approaches to decipher the function of genes in cancer. These studies have allowed us to identify new targets in cancer as well as reasons that cancers become resistant to current therapies. We envision a future where therapies are tailored for specific patients.
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