In Memory of Adam Opiela-Sethi Lab's Gastrointestinal Cancer Research's Fundraising Page

2022 Jimmy Fund Walk
2022 Jimmy Fund Walk

WHY WE'RE FUNDRAISING WITH THE JIMMY FUND WALK TO FIGHT CANCER

 

Led by Joe Opiela, our team walks in memory of and dedication to Adam Opiela, who passed away from metastatic colon cancer on July 25th, 2021, at the all-too-young age of 30.  As part of an inpatient team, I took care of Adam in the beginning of June and then again in July 2021.  He faced many challenges during his clinical course.  I was constantly impressed with his even demeanor, friendly attitude, and kind interactions; we often talked about the NBA playoffs, exchanging notes and analyses.  Please see his obituary to learn more about Adam.  While taking care of Adam, I often felt helpless, and I certainly wish I could offer him more.  Because we believe we can do better for Adam and others, we are committed to basic science and translational colorectal cancer research, hoping to make breakthroughs that will impact lives in positive ways.

The overall goal of the Sethi lab is to combine clinical observations and evaluation of patient samples with rigorous basic science investigation to yield opportunities for impactful translational advances. Our passion for investigative research is fundamentally dependent upon its power to generate a deeper understanding of human disease and ultimately improve patient care. We are particularly committed to defining the fundamental mechanisms underlying colorectal cancer with the hope that such insight will translate into new mechanisms to prevent and treat cancer.

Colorectal cancer is the third most common and second most deadly cancer worldwide; it is also responsible for an alarming trend of increasing incidence among younger individuals.   The colon is the most rapidly renewing tissue in our body, relying on rapid turnover of cells lining the inside of the organ. Stem cells give rise to mature cells that function in digestion and absorption before dying.  These mature cells are constantly being replaced by the next wave of differentiated cells.  Disruption of this natural maturation is a hallmark of colorectal cancer.  Our lab is focused on defining the molecular components that block proper maturation in cancer cells.  We also have designed a unique discovery platform to help us screen thousands of drugs to find the specific agents that overcome this block in maturation.  We strongly believe the next generation of therapeutics will restore proper maturation in colon cancer cells, reprogramming them to live out their natural life cycle. 

In addition to our research efforts, we are dedicated to the mentorship of the next generation of physicians and scientists.  We believe in their potential to change the world. Please see our 2023 Sethi Lab Newsletter and visit the Sethi Lab Website for more details.

 

Thank you for supporting our team in the Jimmy Fund Walk. Together, we can defy cancer!

 

PROGRESS TO GOAL

Raised:$35,932.70
Goal:$35,000
35team members

THANK YOU TO OUR TEAM MEMBERS

C = Team Captain
NAME
AMOUNT RAISED
x162x
x$35,932.70x

THANK YOU TO OUR TEAM DONORS

NAME
AMOUNT
Team Honor Roll
Abhay Singh
Alexis
Andre Abouhala
Andrew Day
$103
Andrew McCarthy
$309
Ann West and Michael Piering
$200
Anonymous
Anonymous
Anonymous
Anonymous
$100
Anonymous
Anonymous
$100
Anonymous
$51
Anonymous
Anonymous
Anonymous
$30
Anonymous
Ari Sacks
$103
Ariell Steel
$30
Ashley Fox
$20
Ben Haycock
$250
Benny Hur
$100
Bernard family
Betsy and Eddie Jacobs in support of Team Opiela Family!!
Bill barke
$300
Bob McDonald
$50
Brett Garofalo
Brian Gavaghan
$103
Caitlin Ghegan
Callinan Family
Carolyn and Eric Broege
Cathy and John Sullivan
Cathy Ehrlich
$250
Colby
Colin M
$103
Connor & Robyn Hatten
Dan P
Danny Gold
$103
DaSilva Family
$100
Dave Fischer & Carol O'Connor-Fischer
Dave Fischer and Carol O'Connor-Fischer
Dave Lynch
$250
David & Jeanne Hill
$103
Dean & Evangeline Calivas
$200
Diego Cadavid
$100
Disney for Martin Callinan
$100
Dobbies
$100
Dr. Jon Opraseuth
$330
Dr. Rob Norman
$103
Ellen and Bob Strunk
$103
Emily and Brian Strunk
$100
Emily Sobiecki
$130
Eric Boole
Family from Northeast PA
Frances & Stephen Sacco
Friends of Adam
$30
George and Patty Cioto
Geraghty Family
Go, BB, go! Love, the Jackson-Chans
Greg Crane
$103
Harrison Everts
in memory of Adam Opiela
Jack & Yupapon McCanna
$100
Jack and Nancy Donnelly
Jackie and Ken Flynn
$30
Jake Kramer
James Wilcox
$100
Jamie and Dewey Parsons
$103
Jane Hill and Andy Dempsey
Jay & Maria
Jayne Donegan
$500
Joanne & Paul Morrissey
$103
Joanne Romanow and Thomas Fennell
$103
John and Cynthia Sobiecki
$206
John and Dorothy Owen
$100
John Barrett
$50
John Sweeney
$103
Jonathan Reisman
$103
Joseph V Charney, Jr. Family
$100
Kathleen Morrissey
$206
Kim and Gil Adams
$103
Laura and Charlie
$309
Leslie Wardrop
$100
Lisa
$50
Lisa Hufnell - Dec
$30
Liz & Kevin Quinn
$103
Mary & Brent Wheeldon
$103
Mary & Walt Posadowski
Matthew & Georgia Calivas
$200
Matthew Wright
$51
Meaghan
Mel and Claire Seibolt
$103
Michael and Martha Festa
Michael Hynes
$100
Mike & Rachel Hayes
Mike Mac & Katherine
Moran
$25
Mr. Brian Strunk
$130
Mr. Damon Calivas
$100
Mr. Jayant Parthasarathy
$7,725
Mr. Jeff Suby
$103
Mr. Joe Terry
Mr. John Fahey
$100
Mr. Matthew Bartolini
$100
Mr. Roth Wilkofsky
$300
Mrs. Cheryl dwyer
$50
Mrs. Shana Sporman
$100
Mrs. Shweta Mahajan Sethi
$35
Ms. Amanda Festa
$103
Ms. Heather Atwood
$300
Ms. Jill Landy
$50
Ms. Joyce Nilsen
$200
Ms. Kimberly Coutinho
$51
Ms. Kristen Fischer
Ms. Lisa Kimball
$206
Ms. Melissa Palchak
$330
Ms. Patricia Posadowski
$103
Ms. Susan Haycock
$103
Nick C.
$103
Nick Kafker
$5,010
Nicole Cisz
Nicole Graham
$50
Nolan Binney
$50
On The Fringe
$725
Pam and Michael Fishlow
$100
Patti and George Whooley
$103
Paul & Tracey Hogan
$103
Paul A Smith
$50
Pauline and Frank Medeiros
Pete Boylan
Peter and Jean Lynch
$100
Peter and Sheree Dolan
Philip & Kathryn Boole
Putterman Family
$100
Quinn Perkson
$100
Richard % Donna Yerganian
$51
Richard Paul DeSorgher
$30
Richie Toni
$300
Rick and Sherri Decina
$100
Rob Kalfus
Robert Castellano
Robert D Mintz
$103
Sarah Steel
Saurabh Abrol
$100
Scott Cook
$515
Sethi Lab
$300
Shereen Berlin
$30
Sophie Vitzthum von Eckstaedt
$20
Stacey Escalante
Stephen Maureen Hayes Family
$100
Steve & Celeste Kramer
$25
Stonegate Group
$200
Sweet Sophie Scents L.L.C.
$100
Tawa Family
$100
The Burrell Family
$103
The Eamer Family
$103
The Giridhars
$206
The LoRusso Family
$100
The Ray Family
$100
The Warren Family
$103
Tom Conlon
$103
Trissa, Tim and Etta Bowen
$51
Virginia Blanford and John Bryant
$51
Virginia Lanigan & Glenn Ticehurst
Woeste Family
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Every dollar raised helps fuel Dana-Farber Cancer Institute's mission.
Together, we can defy cancer!














2023 Boston Marathon Jimmy Fund Walk

2022 Jimmy Fund Walk
2022 Jimmy Fund Walk

In Memory of Adam Opiela-Sethi Lab's Gastrointestinal Cancer Research

 

Led by Joe Opiela, our team walks in memory of and dedication to Adam Opiela, who passed away from metastatic colon cancer on July 25th, 2021, at the all-too-young age of 30.  As part of an inpatient team, I took care of Adam in the beginning of June and then again in July 2021.  He faced many challenges during his clinical course.  I was constantly impressed with his even demeanor, friendly attitude, and kind interactions; we often talked about the NBA playoffs, exchanging notes and analyses.  Please see his obituary to learn more about Adam.  While taking care of Adam, I often felt helpless, and I certainly wish I could offer him more.  Because we believe we can do better for Adam and others, we are committed to basic science and translational colorectal cancer research, hoping to make breakthroughs that will impact lives in positive ways.

The overall goal of the Sethi lab is to combine clinical observations and evaluation of patient samples with rigorous basic science investigation to yield opportunities for impactful translational advances. Our passion for investigative research is fundamentally dependent upon its power to generate a deeper understanding of human disease and ultimately improve patient care. We are particularly committed to defining the fundamental mechanisms underlying colorectal cancer with the hope that such insight will translate into new mechanisms to prevent and treat cancer.

Colorectal cancer is the third most common and second most deadly cancer worldwide; it is also responsible for an alarming trend of increasing incidence among younger individuals.   The colon is the most rapidly renewing tissue in our body, relying on rapid turnover of cells lining the inside of the organ. Stem cells give rise to mature cells that function in digestion and absorption before dying.  These mature cells are constantly being replaced by the next wave of differentiated cells.  Disruption of this natural maturation is a hallmark of colorectal cancer.  Our lab is focused on defining the molecular components that block proper maturation in cancer cells.  We also have designed a unique discovery platform to help us screen thousands of drugs to find the specific agents that overcome this block in maturation.  We strongly believe the next generation of therapeutics will restore proper maturation in colon cancer cells, reprogramming them to live out their natural life cycle. 

In addition to our research efforts, we are dedicated to the mentorship of the next generation of physicians and scientists.  We believe in their potential to change the world. Please see our 2023 Sethi Lab Newsletter and visit the Sethi Lab Website for more details.

 

Thank you for supporting our team in the Jimmy Fund Walk. Together, we can defy cancer!

 

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